NWBO keeps letting the perfect be the enemy of the good enough. There will always be another approach to try and another improvement to make but after a certain point it is time to go with what you have.
As the moribund state of DCVax Prostate suggests, anytime a moment of truth approaches, NWBO always finds a way to not move forward.
Individually, each action like delaying the End of DCVax L Phase 3 to wait on OS instead of the planned primary endpoint of PFS can be defended and even seems prudent.
But when you step back and look at the pattern and results of these actions, it is hard to defend especially when the objective reality for shareholders is so dire.