Preferential invasion of mitotic cells by Salmonella reveals that cell surface cholesterol is maximal during metaphase António J. M. Santos, Michael Meinecke, Michael B. Fessler, David W. Holden, Emmanuel Boucrot J Cell Sci 2013 126: 2990-2996; doi: 10.1242/jcs.115253
This increase was due not only to the rise in global cell cholesterol levels along the cell cycle but also to a transient loss in cholesterol asymmetry at the plasma membrane during mitosis. We measured that cholesterol, but not phosphatidylserine, changed from a ~20:80 outer:inner leaflet repartition during interphase to ~50:50 during metaphase, suggesting this was specific to cholesterol and not due to a broad change of lipid asymmetry during metaphase.
Wook,
This is what I call, "taking away the keys that drive parthenogenesis".