Avid Bioservices Inc (CDMO)

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Preferential invasion of mitotic cells by Salmonella reveals that cell surface cholesterol is maximal during metaphase
António J. M. Santos, Michael Meinecke, Michael B. Fessler, David W. Holden, Emmanuel Boucrot
J Cell Sci 2013 126: 2990-2996; doi: 10.1242/jcs.115253

This increase was due not only to the rise in global cell cholesterol levels along the cell cycle but also to a transient loss in cholesterol asymmetry at the plasma membrane during mitosis. We measured that cholesterol, but not phosphatidylserine, changed from a ~20:80 outer:inner leaflet repartition during interphase to ~50:50 during metaphase, suggesting this was specific to cholesterol and not due to a broad change of lipid asymmetry during metaphase.

Wook,

This is what I call, "taking away the keys that drive parthenogenesis".

Bavi 2.0 + Statin = ? Common Cold?

All the best,
John