Replies to post #53755 on NorthWest Biotherapeutics Inc (NWBO)

[longfellow95]

RK. Not correct.

Please read the report from the Jan 26 presentation.
The link is on the home page of the companies website.

Quote:-

''DC-Vax Direct may help increase percentage of patients responding to checkpoint inhibitors.''

So, as I said to Austin, the idea of some sort of trial partnership, is still very much on the cards.

[highwayman4life]

Odds for success would improve dramatically in their favor, in my opinion, if they could combine with an agent that combats immunosuppression.

http://www.immunotherapyofcancer.org/content/pdf/2051-1426-2-S3-P61.pdf

Intratumoral injection of activated, autologous dendritic cells is safe and feasible. The accumulation of immune cells in tumor biopsies suggests that these injections have the potential to successfully change the tumor microenvironment from immunosuppressive to one that is conducive to the induction of anti-tumor immune responses. (boy is there alot of good info on dc vaccines overcoming an immunosuppressive environment all by themselves:-)) Normalization of the CD4:CD8 T cell ratio in circulation demonstrates the potential for systemic effects of this novel therapeutic approach.

Rk, do you ever take any accountability for the numerous unsubstantiated, unfounded, speculatory, midleading posts that can easily be disproved? You stated Direct is a monotherapy or won't be used as a combo therapy, right? That was a tough one to disprove. Sure would be nice to see you post something new.

TTFN luv, may you continue to ramble on