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Re: Rkmatters post# 53755

Sunday, 02/14/2016 5:39:54 PM

Sunday, February 14, 2016 5:39:54 PM

Post# of 824062

Odds for success would improve dramatically in their favor, in my opinion, if they could combine with an agent that combats immunosuppression.



http://www.immunotherapyofcancer.org/content/pdf/2051-1426-2-S3-P61.pdf

Intratumoral injection of activated, autologous dendritic cells is safe and feasible. The accumulation of immune cells in tumor biopsies suggests that these injections have the potential to successfully change the tumor microenvironment from immunosuppressive to one that is conducive to the induction of anti-tumor immune responses. (boy is there alot of good info on dc vaccines overcoming an immunosuppressive environment all by themselvessmile) Normalization of the CD4:CD8 T cell ratio in circulation demonstrates the potential for systemic effects of this novel therapeutic approach.

Rk, do you ever take any accountability for the numerous unsubstantiated, unfounded, speculatory, midleading posts that can easily be disproved? You stated Direct is a monotherapy or won't be used as a combo therapy, right? That was a tough one to disprove. Sure would be nice to see you post something new.

TTFN luv, may you continue to ramble on

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