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Replies to #29639 on Biotech Values
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jellybean

06/05/06 11:41 AM

#29640 RE: poorgradstudent #29639

the problem with shorting the stock now is that anything resembling success will drive it up. So you need to wait and watch for those upswings. Then you short like mad.
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gofishmarko

06/05/06 2:09 PM

#29648 RE: poorgradstudent #29639

Re: Troponin I is a euphemism for infarction / death of cardiomyocytes.

PGS,

Do you (or anyone else) know if troponin levels are usually measured in clinical trials , paricularly cancer trials?

The reason I ask is that it seems to me that in certain types of trials it might be reasonable to expect , and tolerate , transient elevations in troponin or other markers of organ tissue damage. For example , the anti-CTLA4 mab treatments have been found to be most effective when there is evidence of autoimmune-type side effects , as I'm sure you know. I would expect other cancer immunotherapies might be similar in this regard , and that a risk/benefit calculation might favor the treatment as long as the damage is transient and/or reversible.
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winvestor2

06/06/06 10:00 AM

#29704 RE: poorgradstudent #29639