Although the viruses themselves are very different, it’s worth noting that Truvada is almost never used by itself in HIV. Truvada is conceptually similar to VRUS’ 2-drug HCV combo insofar as it consists of a purine nuke and a pyrimidine nuke with non-overlapping barriers to resistance.
“The efficient-market hypothesis may be the foremost piece of B.S. ever promulgated in any area of human knowledge!”