NorthWest Biotherapeutics Inc (NWBO)

[CherryTree1]

Sounds like NWBO DCVAX patent infringement.
Even if DOC 1021 is a "Double Loaded" dendritic cell vaccine has additional steps it as to the process to incorporate more lysate it means it is an enhancement to NWBO's patents not a completely new invention so the would have to pay NWBO to license their already patented steps or NWBO can simply prevent them from producing it.

If you don't believe me here is what AI has to say about it:

Yes, you can patent an improvement, but the original patent owner still owns their original patent and you'd likely need their permission (a license) to sell your improved product because it incorporates their patented invention; you'll have your own patent for the improvement, but they have rights to the base technology, creating a situation where both parties might need licenses from each other.
How it Works
Your Improvement is Patentable: If your improvement is novel, useful, and non-obvious, you can get your own patent (a "improvement patent") for the new features you added.
Infringement Risk: You cannot legally make, use, or sell your improved product without a license from the original patent holder if your invention still uses the core elements of their existing patent.
Cross-Licensing: The original owner can't make or sell your improved version without a license from you (for your improvements), and you can't sell it without a license from them (for the base invention). This often leads to cross-licensing agreements.
Your Patent Covers the Difference: Your patent protects the new, improved parts, not the entire original invention.