| Followers | 14 |
| Posts | 346 |
| Boards Moderated | 0 |
| Alias Born | 10/18/2023 |
Thursday, November 20, 2025 7:27:24 PM
Sure, that is an option.
Or just dilute to 150mm shares and run a P3 trial. Everyone just chills out for a while and see what happens. Even at 150mm shares, an oral disease-modifying pill for 50% of the AD population is worth more than a couple of shekels.
Or, find a partner. They'll value it as they would any P3-stage company with two promising pipeline candidates for major indications. Most likely the range is from $700mm - $3.5B. Do you think if Chris M offers a 50/50 revenue split for $3.5B there wouldn't be offers?
Or, as I jokingly suggested before, spend more money lobbying the FDA and politicians. Ultimately, politicians and regulators will respond to the people's wishes if the pressure is intense enough. That's why it would be nice to hear from the company what this would have cost had it been approved. When people realize they can take a pill for $7000 or an infusion for $30,000, the public demand increases and that pressure is often enough --- at least with the current administration's pay -to -play politics.
Or they could throw in the towel and give up as many here seem resigned will happen. I am not one of them. I didn't love the idea of going for it with a P2/3 pivotal trial and stellar but limited data. But here we are. I look forward, and I still see a lot of ballgame left to play. The stock price is what it is at any given time. The drug either works or it doesn't and worst case we find out in 2 or 3 more years. Best case we find out in April if the EMA has a change of heart. Still too early to say what happens. But if Dr. M goes, and he may, who specifically should replace him?
Or just dilute to 150mm shares and run a P3 trial. Everyone just chills out for a while and see what happens. Even at 150mm shares, an oral disease-modifying pill for 50% of the AD population is worth more than a couple of shekels.
Or, find a partner. They'll value it as they would any P3-stage company with two promising pipeline candidates for major indications. Most likely the range is from $700mm - $3.5B. Do you think if Chris M offers a 50/50 revenue split for $3.5B there wouldn't be offers?
Or, as I jokingly suggested before, spend more money lobbying the FDA and politicians. Ultimately, politicians and regulators will respond to the people's wishes if the pressure is intense enough. That's why it would be nice to hear from the company what this would have cost had it been approved. When people realize they can take a pill for $7000 or an infusion for $30,000, the public demand increases and that pressure is often enough --- at least with the current administration's pay -to -play politics.
Or they could throw in the towel and give up as many here seem resigned will happen. I am not one of them. I didn't love the idea of going for it with a P2/3 pivotal trial and stellar but limited data. But here we are. I look forward, and I still see a lot of ballgame left to play. The stock price is what it is at any given time. The drug either works or it doesn't and worst case we find out in 2 or 3 more years. Best case we find out in April if the EMA has a change of heart. Still too early to say what happens. But if Dr. M goes, and he may, who specifically should replace him?
Recent AVXL News
- Form 8-K - Current report • Edgar (US Regulatory) • 05/22/2026 12:15:26 PM
- Anavex Life Sciences Receives Expected Nasdaq Delinquency Notification • GlobeNewswire Inc. • 05/22/2026 12:00:00 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 05/15/2026 08:15:25 PM
- Form 3 - Initial statement of beneficial ownership of securities • Edgar (US Regulatory) • 05/14/2026 08:15:30 PM
- Form NT 10-Q - Notification of inability to timely file Form 10-Q or 10-QSB • Edgar (US Regulatory) • 05/11/2026 08:30:22 PM
- CEO Transition and Delayed SEC Filing Put Anavex (AVXL) Leadership Changes in Focus • IH Market News • 05/06/2026 02:52:36 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 05/06/2026 11:04:59 AM
- Anavex Life Sciences Board of Directors Appoints Former Senior Vice President of Clinical Development Terrie Kellmeyer, PhD, as Interim Chief Executive Officer • GlobeNewswire Inc. • 05/06/2026 11:00:00 AM
- Form 3 - Initial statement of beneficial ownership of securities • Edgar (US Regulatory) • 05/01/2026 11:18:47 PM
- Anavex Life Sciences Highlights New Scientific Findings on Shared Biology Between Autism and Alzheimer’s Disease • GlobeNewswire Inc. • 04/14/2026 11:30:00 AM
- Anavex Life Sciences to Present at the 25th Annual Needham Virtual Healthcare Conference • GlobeNewswire Inc. • 04/07/2026 11:30:00 AM
- Anavex withdraws EU approval filing for Alzheimer’s therapy • IH Market News • 03/30/2026 12:39:26 PM
- Anavex Life Sciences Provides Comprehensive Regulatory Update • GlobeNewswire Inc. • 03/30/2026 11:30:00 AM
- Form 8-K - Current report • Edgar (US Regulatory) • 03/25/2026 08:06:00 PM
- Anavex withdraws EU marketing application for Alzheimer’s therapy blarcamesine • IH Market News • 03/25/2026 02:06:58 PM
- Anavex Life Sciences Provides Update on Regulatory Review in the EU for Blarcamesine to Treat Early Alzheimer’s Disease • GlobeNewswire Inc. • 03/25/2026 11:30:00 AM
- Anavex Life Sciences Presents New Data from its AD-004 Phase IIb/III Trial at AD/PD 2026 Conference Demonstrating Consistent Correlation Between the Treatment Effect of Oral Blarcamesine and Preservation of Brain Volume in Early Alzheimer’s Disease • GlobeNewswire Inc. • 03/23/2026 11:30:00 AM
- New Scientific Findings Highlight Hypothesis of Autophagy Failure as a Precursor of Amyloid Beta and Tau Pathology in Alzheimer’s Disease • GlobeNewswire Inc. • 03/20/2026 11:30:00 AM
- Anavex Life Sciences Presents Significant Treatment Effects of Blarcamesine in New Advanced Alpha-Synuclein Model of Parkinson’s Disease at AD/PD 2026 Conference • GlobeNewswire Inc. • 03/17/2026 11:30:00 AM
- Anavex Life Sciences to Present at the Citizens Life Sciences Conference • GlobeNewswire Inc. • 03/03/2026 12:30:00 PM
- Anavex Life Sciences to Present at the 46th TD Cowen Annual Health Care Conference • GlobeNewswire Inc. • 02/25/2026 12:30:00 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 02/25/2026 11:07:01 AM
- Anavex Life Sciences Appoints Seasoned Healthcare Leader to Board of Directors • GlobeNewswire Inc. • 02/23/2026 12:30:00 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 02/09/2026 09:40:27 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 02/09/2026 12:31:17 PM
