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Re: boi568 post# 501774

Tuesday, 09/30/2025 2:41:56 PM

Tuesday, September 30, 2025 2:41:56 PM

Post# of 519116
This really is as silly a question as I've come to expect here. Regardless, here is the answer.

My chance of CMA is 75% - possibly too generous and certainly much much better than Doc's.

The OLE and post hoc analysis is tantalising. The p-vals are all based on either comparing OLE early and late starters or post hoc analysis - as impressive as they are, they are not derived in a controlled context.
A lot has been learned, which all is very useful for designing a confirmatory P3 PM trial - the one Anavex should have initiated as they said they would back early 2023.
Done right such a trial IMO has a high likelihood of success.

The longer we wait, the sooner we will get rich!

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