SiNtx Technologies Inc (SINT)

[boston745]

Joe, Im still waiting for you to answer my questions about Titanium as a neurotoxin and thus the need for Si3n4 to coat/replace it. You've gone quiet almost as if you dont want to answer the question.

Now what do you think about Titanium being a Neurotoxin and the need to coat it/replace it with Si3N4

Potential neurotoxicity of titanium implants: Prospective, in-vivo and in-vitro study

Titanium dioxide (TiO2) is a frequently used biomaterial, particularly in orthopedic and dental implants, and it is considered an inert and benign compound. This has resulted in toxicological scrutiny for TiO2 in the past decade, with numerus studies showing potential pathologic downstream effects. Herein we describe case report of a 77-year-old male with subacute CNS dysfunction, secondary to breakdown of a titanium-based carotid stent and leading to blood levels 1000 times higher (3 ppm) than the reported normal.

Rats bearing titanium implants or intravascularly treated with TiO2 nanoparticles (TiNP) exhibited memory impairments. A human blood-brain barrier (BBB) in-vitro model exposed to TiNP showed paracellular leakiness, which was corroborated in-vivo with the decrease of key BBB transcripts in isolated blood vessels from hippocampi harvested from TiNP-treated mice. Titanium particles rapidly internalized into brain-like endothelial cells via caveolae-mediated endocytosis and macropinocytosis and induced pro-inflammatory reaction with increased expression of pro-inflammatory genes and proteins. Immune reaction was mediated partially by IL-1R and IL-6. In summary, we show that high levels of titanium accumulate in humans adjacent to orthopedic implants, and our in-vivo and in-vitro studies suggest it may be neurotoxic.

Quote Source:
https://www.sciencedirect.com/science/article/abs/pii/S0142961221003951

========================================

Electromagnetic fields, metal implant corrosion, and dis-ease it causes


https://i.imgur.com/nLg7SXT.jpg

Cancer-Causing Effects of Orthopaedic Metal Implants in Total Hip Arthroplasty
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11011042/

Oral Cancer around Dental Implants: Are the Clinical Manifestations and the Oncogenic Mechanisms Unique?
https://www.intechopen.com/chapters/79298

https://investorshub.advfn.com/boards/read_msg.aspx?message_id=172932779

========================================

For continued coverage of significant Airplane malfunctions and why Sintx Si3N4 aerospace products are needed goto my research board. 42 passenger plane malfunctions since December 22nd..
https://investorshub.advfn.com/Bostons-research-43724

Here is a collection of my research going over multiple subjects including Sintx connections with Zimmer Biomet, Solventum, Morgan Ceramics, & NP Aerospace. Includes other research topics as well.
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=175357996

========================================

We already know Sintx and Morgan were working together. If there is going to be some sort of NP/Sintx merger, that just solidifies it. We also know Zimmer Biomet and Sintx have had a long standing relationship (going on 20 years) so as long as Sintx components for Arthroplasty are any good, Zimmer Biomet will come out from behind the curtain. With ZB comes ZimVie and I believe Solventum because of Bryan Hanson. Leaving only Cardinal Health which is suggested by Sintx hiring of Joseph Palomo who joined Sintx from Cardinal Health R&D division.

Morgan Ceramics = Aerospace products
Zimmer Biomet = Arthroplasty oriented products
ZimVie = Dental?
Solventum = Wound Care, Catheters, & possibly Cancer treatment products.
Ned Medical = Microspheres for cancer treatment
Cardinal Health = PPE & Medical protection apparel.
NP Aerospace = Armor plates & other possible products connected to TA&T.

========================================

Markets Si3n4/Sintx Ceramics can be used in (not comprehensive)

Otho Market = $64 billion
Personal Protective Equipment market = $79.53 billion
Global Catheter market = $55bn
Antibacterial market = $44.5bn
Wound Care market = $22.25bn
Biosensors Market = $28.9bn
Condom Market = $11.6bn
Dental Implant market = $4.99bn
Armor Materials Market = $13.59bn
Cancer Treatment (microspheres) = $5-$15bn

Total = $330bn-340bn

Sources:
https://web.archive.org/web/2024040...ogger.blogspot.com/2011/05/whos-next.html?m=1
https://orthospinenews.com/2021/01/...y-2025-as-acquisitions-surge-says-globaldata/
https://www.grandviewresearch.com/industry-analysis/personal-protective-equipment-ppe-market
https://www.grandviewresearch.com/industry-analysis/catheters-market-analysis
https://www.grandviewresearch.com/industry-analysis/wound-care-market
https://www.grandviewresearch.com/industry-analysis/biosensors-market
https://www.grandviewresearch.com/industry-analysis/condom-market
https://www.mordorintelligence.com/industry-reports/armor-materials-market
https://www.grandviewresearch.com/industry-analysis/dental-implants-market
https://www.youtube.com/watch?v=KeSa5vCj6Kw
https://www.grandviewresearch.com/industry-analysis/personal-protective-equipment-ppe-market
https://www.grandviewresearch.com/industry-analysis/catheters-market-analysis
https://www.grandviewresearch.com/industry-analysis/wound-care-market
https://www.grandviewresearch.com/industry-analysis/biosensors-market
https://www.grandviewresearch.com/industry-analysis/condom-market
https://www.mordorintelligence.com/industry-reports/armor-materials-market
https://www.grandviewresearch.com/industry-analysis/dental-implants-market
https://www.youtube.com/watch?v=KeSa5vCj6Kw