NorthWest Biotherapeutics Inc (NWBO)

[Doc logic]

I should have clarified more. DCVax is a vaccine that identifies targets and presents them to T-cells which then go on the hunt for those targets. The problem is that many of the remaining targets in the tumor bed or small clusters of cells forming metastasis are hiding and need to be exposed better. Methylated status keeps targets exposed longer and unmethylated much less time. By the time L is given a chance to work, many cancer cells are hiding again or are not susceptible to chemo/rad. Antibody drug conjugates will be theoretically safer than chemo/rad and keep targets exposed at the right time for L activated T-cells to identify their targets more easily. Direct can do all this on its own for the most part but if it does need help, this might be where it comes from, at least that’s what big pharma hopes for anyway; ). Best wishes.