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Re: meirluc post# 558719

Wednesday, 01/11/2023 10:46:46 PM

Wednesday, January 11, 2023 10:46:46 PM

Post# of 701110
Read the peer-reviewed article that challenges NWBO's trial conclusions. They are neurooncologists and frame the cherry-picking better than I -- read it yourself as the Regulators will.

https://academic.oup.com/neuro-oncology/advance-article/doi/10.1093/neuonc/noac281/6958519?login=false

The protocol was for a PFS primary endpoint -- cross-over was intended as salvage medication for those that don't respond. It caused a confounding of the nOS by repeated dosing of cherry-picked patients (read the article). The external comparators didn't cherry-pick like NWBO did -- that's how you could improve you OS -- healthier patients to start.
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