Wednesday, January 11, 2023 10:36:38 PM
HyGro, if the patients in the DCVax-L trial were cherry picked, why was the mOS of the 131 unmethylated patients in the treatment arm (about 40% of the patients in the trial), only 0.3 months longer than the mOS of the ECAs? This documents that there was no cherry picking in this trial
Furthermore, if DCVax-L is ineffective, it would not matter if you administered patients one dose or multiple doses and by the way, the original protocol did call for multiple doses of DCVax-L and the investigators followed that protocol. So why would anyone object to the protocol and decide that the patients should only receive DCVax-L once?
Finally, the UCLA combo trial while, incomplete, demonstrates that about 60% of
the patients receiving the combo treatment, have already survived 800(+) days past their progression. Whatever happens to those survivors in the next months or years, that trial is already a success because it strongly suggests that without the DCVax-L component of the combo treatment, such spectacular survival results would not be possible. This is obvious because other treatments (i.e. keytruda, poly ICLC etc.) have so far not obtained such long survival results.
Furthermore, if DCVax-L is ineffective, it would not matter if you administered patients one dose or multiple doses and by the way, the original protocol did call for multiple doses of DCVax-L and the investigators followed that protocol. So why would anyone object to the protocol and decide that the patients should only receive DCVax-L once?
Finally, the UCLA combo trial while, incomplete, demonstrates that about 60% of
the patients receiving the combo treatment, have already survived 800(+) days past their progression. Whatever happens to those survivors in the next months or years, that trial is already a success because it strongly suggests that without the DCVax-L component of the combo treatment, such spectacular survival results would not be possible. This is obvious because other treatments (i.e. keytruda, poly ICLC etc.) have so far not obtained such long survival results.
Recent NWBO News
- How Advanced Drug Delivery Could Improve Existing Cancer Treatments • GlobeNewswire Inc. • 06/01/2026 12:30:00 PM
- CNS Drug Delivery Breakthroughs Unlock Significant Biotech Market Opportunities • InvestorsHub NewsWire • 05/11/2026 01:00:00 PM
- CNS Drug Delivery Breakthroughs Unlock Significant Biotech Market Opportunities • GlobeNewswire Inc. • 05/11/2026 12:30:00 PM
- Northwest Biotherapeutics Appoints Dr. Annalisa Jenkins As Strategic Adviser To Advance Dendritic Cell Cancer Vaccine Platform • PR Newswire (US) • 04/30/2026 04:38:00 PM
- Northwest Biotherapeutics Appoints Dr. Annalisa Jenkins As Strategic Adviser To Advance Dendritic Cell Cancer Vaccine Platform • PR Newswire (US) • 04/30/2026 04:30:00 PM
- Northwest Biotherapeutics Announces Establishment Of the Company's Own Dedicated Leukapheresis Clinic • PR Newswire (US) • 04/21/2026 01:30:00 PM
- Northwest Biotherapeutics Announces Establishment Of the Company's Own Dedicated Leukapheresis Clinic • PR Newswire (US) • 04/21/2026 01:30:00 PM
- Form EFFECT - Notice of Effectiveness • Edgar (US Regulatory) • 04/21/2026 04:15:08 AM
- Form POS AM - Post-Effective amendments for registration statement • Edgar (US Regulatory) • 04/16/2026 09:25:30 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 04/07/2026 04:30:50 PM
- Form NT 10-K - Notification of inability to timely file Form 10-K 405, 10-K, 10-KSB 405, 10-KSB, 10-KT, or 10-KT405 • Edgar (US Regulatory) • 03/31/2026 09:04:37 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 01/15/2026 10:06:20 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 01/02/2026 10:14:59 PM
- Form DEF 14A - Other definitive proxy statements • Edgar (US Regulatory) • 11/28/2025 09:43:27 PM
- Form 424B5 - Prospectus [Rule 424(b)(5)] • Edgar (US Regulatory) • 11/25/2025 10:23:07 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 11/20/2025 09:26:03 PM
- Form PRE 14A - Other preliminary proxy statements • Edgar (US Regulatory) • 11/19/2025 09:15:48 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 11/14/2025 09:44:21 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/31/2025 04:29:10 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/30/2025 08:40:05 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/24/2025 04:28:38 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/14/2025 06:22:26 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 08/14/2025 09:00:38 PM
- Form 424B5 - Prospectus [Rule 424(b)(5)] • Edgar (US Regulatory) • 07/01/2025 09:04:38 PM
