Wednesday, October 12, 2022 12:29:38 PM
DCVax does a plasmapheresis, makes DCs, makes a lysate from the tumor, puts the two together. Simple. Why go through a Rube Goldberg process to find a bunch of proteins, make an mRNA sequence for each, then shoot that into a patient and hope it finds DCs in your body, hope those DCs take up the mRNA and transcribe it into the same proteins you already have, present them on their surface, and hope T cells are recruited?
And why do all of this when you already have Keytruda showing that in combo with DCVax the two fight GBM better than either alone? Well, maybe when you try to bullshit a woman like LP into selling or partnering on the cheap?
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