NorthWest Biotherapeutics Inc (NWBO)

[SkyLimit2022]

The MC at the time of acquisition is hard to predict for any company considering how quickly it can rise. For DCVax, the big picture is much more interesting and enlightening: What is the technology worth as a platform and in combo? Years of safety/efficacy data from 94 trial sites globally and years of compassionate use safety/efficacy data are together the most reliable indicators of value. DCVax is already efficacious, but further development of the technology, innovations of methods of use, and indications beyond GBM are valuable beyond measure.

Additionally, we need to factor in the unmet need of rGBM. The rGBM data was a breakthrough discovery as survival was doubled for a stage of the disease for which there is no treatment to extend life.

Furthermore, the capacity to manufacture at large scale is another amazing factor to keep in mind.

Immunotherapy is the future of cancer treatment. FDA believes without question that cell-based science is worth their support and will ensure that the United States will lead the world in technologies to better address cancer, extend life, and ultimately reach a cure.

Steinman’s discovery of the dendritic cell won the Nobel Prize some years ago, and Dr. Liau’s work built upon his discovery and led to the discovery of how the dendritic cell-based technology can extend life for the deadliest cancer known to humankind. Dr. Liau deserves a Nobel Prize for her work and has already earned a worldwide reputation as an immunotherapy pioneer and scientific genius.

Dr. Liau is building upon the discoveries of scientists who have preceded her in time, and she is enlightening the future of immunotherapy with her groundbreaking work.

“I will respect the hard-won scientific gains of those physicians in whose steps I walk, and gladly share such knowledge as is mine with those who are to follow.” —Hippocratic Oath

https://www.livescience.com/16354-nobel-prize-medicine-2011-immune-research.html

https://virtualtrials.org/dcvax.cfm

https://soc-neuro-onc.org/

https://connect.uclahealth.org/2022/09/14/brain-cancer-discovery-clinical-trials/

https://www.fda.gov/science-research/advancing-regulatory-science/fda-nih-joint-leadership-council-charter

https://connect.uclahealth.org/2021/03/22/ucla-received-590-million-in-nih-funding-second-highest-total-for-academic-medical-centers-in-2020/

https://www.fda.gov/about-fda/fda-organization/richard-pazdur

https://www.annalsofoncology.org/article/S09237534(22)00006-0/fulltext

https://www.fda.gov/drugs/news-events-human-drugs/50-years-progress-treating-patients-cancer

https://www.webmd.com/cancer/cancer-in-context/video/richard-pazdur

https://www.onclive.com/view/pazdur-followed-the-pathway-of-greatest-resistance-to-the-fda