NorthWest Biotherapeutics Inc (NWBO)

[biosectinvestor]

You have misstated the importance of the term clinically meaningful. Clinically meaningful is literally the benchmark for a confirmation of real change in the patient’s condition caused in a clinical trial by the intervention.

It seems rather that they spoke correctly in saying 1) the result was clinically meaningful; and 2) statistically significant. Clearly there was a very large change in outcome for patients, some more than others but quite significant. You measure that by statistical measure. Clinically significant is a nice way to cross the two ideas, but the reality is that they accomplished both measures, as stated on their slide. They were precise. Stating it as clinically significant and statistically significant is kind of repetitive. Though I imagine they could have said that if they had wanted to say it. But the measure for “significance” is statistical. The clinical measure also is the statistical difference but also things like quality of life and other measures that are also communicated, without their having to cross the two ideas into one idea that is less clear.