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Re: MI Dendream post# 421724

Friday, 11/26/2021 11:06:18 AM

Friday, November 26, 2021 11:06:18 AM

Post# of 701881
MI, I'm 99% certain that the trial enrollment was halted due to pseudoprogression, and if it turned out patients were in fact getting worse, the trial would have failed. It turns out pseudeoprogression is very common with immunotherapy, it just wasn't very well understood in 2015. NWBio could not say that it was pseudoprogression and that the patients were actually responding to treatment without compromising the integrity of the trial. (LP said "they turned a good thing into bad") This trial is an incredible success!!!
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936240/
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