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Re: georgejjl post# 294222

Tuesday, 01/26/2021 12:39:31 PM

Tuesday, January 26, 2021 12:39:31 PM

Post# of 462262
Some items regarding Avatar:

ANAVEX2-73 Study in Patients With Rett Syndrome (AVATAR)

Estimated Primary Completion Date : January 31, 2021
Estimated Study Completion Date : February 28, 2021


Expect Avatar completion dates to be accurate, as these were the only Avatar record items updated at the last update (end of November).

OK, if given that completion dates are accurate, then what does that mean in terms of schedule?

It was curious that the Avatar enrollment status was not updated on the Dec 28 CC, as this trial was the one next up to have full enrollment and complete. Yet the AD trial enrollment, was updated, and it will not complete for a year. Why?

Working back from Jan31 Primary Completion (last patient, last data collected) 7 weeks, would put the last patient enrolled/accepted at Dec.7...12 days after the record update. Interesting..12 days schedule 'padding' or just coincidence?

On Dec28, the enrollment should have been complete, for trial Primary completion to end Jan31.

Dr.M just keeping the cards very close to his vest?

Almost end of January and no word of FDA meeting date. Is Dr.M waiting for the Avatar high dose data, so he can have both high and low for the meeting?

Ana estimates 33 patient results will take all of February.
March+ could be very interesting! We will be there soon!

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