Lykiri/flipper et al., the link Lykiri posted on ICD that involves dead cells/apoptosis that becomes antigen cargo for DC vaccines while it subverts immunosuppressive environment is very interesting to note. Thanks to Dr. B, I think Direct is exactly designed based on this concept. Glad 5-ALA resection technique was used in the last several German patients in the L trial that provided tons more of antigen cargo to the autologus L vaccine already prepared. I now clearly understood this part of the L trial now. I think this portion of the L trial is used as Phase 4 to confirm the effectiveness of the therapy. We are sure good to go and the month of November will bring good fortune to all of us and of course good health for the cancer patients all over the world.
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