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Tuesday, 04/17/2018 3:29:07 PM

Tuesday, April 17, 2018 3:29:07 PM

Post# of 518348
Highlights of the shareholder meeting

1. Missling is highly enthusiastic about the results for alz so far. Long term users are showing sustained improvement and or stability, both of which no other alz drug can do.

2. Both Ariana and Illumina found specific markers that determine whether or not a patient will respond to 273. Combined they should greatly increase the prospects for picking people who will respond very well in the p3 for alz. This will also help the other tests.

3. Stephen Toutain is a key hire. He will enable AVXL to take the Rett treatment directly to market. He is very enthusiastic about AVXL's potential to help the Rett girls.

4. All of our tests will be designed to enable AVXL to apply for accelerated approval. Missling is always thinking about the best way to convince the govt to sign on for early approval.

5. They have precise data on the optimal effective dose.

6. Cash is $28 million, enough to fund the company for 2 years.

7. FDA relations are very good and they are actively working with AVXL to design a trial that will reach conclusions and allow for expedited approval based on hitting the FDA targets.


Bring on Denner!

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