Sunday, February 18, 2018 9:10:42 AM
So if DC-Vax is a failure why would Linda Liau et al. continue trials to determine why some patients respond and other do not?
First, failure of a trial does not always imply the drug is a failure. See Herceptin for a classic example of a drug that failed a key mid stage trial yet is now a blockbuster.
Oh, and what saved Herceptin was the understanding of what patients responded.
Second, I would not that both these were published in late '16. The trials could well have started last decade.
Even most all bears acknowledge that DC vaccines are somewhat effective. It is finding the correct "secret sauce" and patient selection that could make one a winner.
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