Sunday, September 25, 2016 9:26:27 AM
I will put in my 2 cents and go back to lurking. I can only take some facts and speculate like everyone else.
Screening halt. We know it is not safety based on what was said at a shareholders meeting. We know it is not futility based on LL's video of patients living longer due to cross over and comparisons will come down to looking at folks receiving vaccine early vs later.
My only conclusion is they are letting the trial extend to see if the vaccine should be administered earlier or a data set to set up a new open label trial where the patient gets earlier access to the vaccine. So my speculation is the vaccine works because of lack of number of events but trying to get more out of the data assembled for moving forward beyond approval.
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