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Re: Stillwell888 post# 71589

Monday, 08/29/2016 6:39:04 AM

Monday, August 29, 2016 6:39:04 AM

Post# of 817888
Agree, update on L info arm is quite likely.
I suppose some feedback on eventing rate and projected date for data unblinding is being a bit hopeful.
Don't expect any more than that re. L. It would be bad form anyway to blow Andrew Gengos completely out of the water, a couple of hours after he has presented.

Nevertheless, we know that Linda has had this pencilled in for at least 5 months as speaker, and the company co-sponsoring the whole event.

So I do expect something of significance, such as announcing partnerships, straight after reporting positive Direct data


And to elucidate on:-

"The Company has undertaken extensive analyses of data from the Phase I portion of the Phase I/II trial of DCVax-Direct for all types of inoperable solid tumors. The Phase I portion of the study involved 3 different dose levels, 2 different product formulations, 13 different cancers, several modes of image guidance for treatment administration and multiple measures related to immune system activation. Analyses of this data have found some novel, unexpected and encouraging results that are of significance for further trials. Also, the Company and physician advisors have completed clinical analyses and preparations for injection of multiple tumors in multiple different tissue locations (going well beyond what any other known trial has undertaken), as well as a greater number of treatment cycles, for the upcoming Phase II portion of the trial. In addition, the Company and its manufacturer, Cognate BioServices, Inc. (“Cognate”) have completed a lengthy program of development work to further optimize the DCVax-Direct investigational product."


And there is the possibility of some sort of tie-up with Abzena, which has previously been discussed.


Not sure whether these SMI conferences have been streamed live in previous years. There certainly is a Youtube video available from last years conference, which I'm going to review.
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