Yes, science folks please chime in. I like Pyrr's take "necrosis". Did Flip go fishing?
I stumbled across this when attempting to make better sense of the SITC title. It's from 2010, but it's helpful in explaining what the title could mean. It does not reference NWBO Afford. But I think we may soon find cancer's lease in the body could be up, and cancer doesn't get to purchase the host.
Inhibiting the Inhibitors: Evaluating Agents Targeting Cancer Immunosuppression
Nevertheless, the fact remains that tumors progress in immunologically competent hosts in the face of existing and measurable anti-tumor immune responses and despite various oncologic therapies administered to cancer patients. Thus, although the components necessary for mounting an effective anti-tumor immune response are present in patients with cancer, the host usually fails to arrest tumor progression.
and
Given the multiplicity of known mechanisms involved in this process and the prevailing practice of treating advanced metastatic disease with immune therapies, this lack of association between immune and clinical responses to therapy is not surprising.
What a difference four years in immunotherapy makes.