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DewDiligence

10/05/13 3:08 PM

#167607 RE: pcrutch #167605

ABBV/ENTA—I expect SVR12 >=95% for SAPHIRE-1 and SVR12>=90% for SAPHIRE-2 in the immediate-treatment arms.

In each trial, I expect the immediate-treatment arm and the delayed-treatment (control) arm to have roughly the same SVR rate, although the delayed-treatment arms could have slightly lower SVR rates due to the possibility of non-drug-related discontinuation during the 12-week placebo period.
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DewDiligence

10/06/13 12:40 PM

#167623 RE: pcrutch #167605

ABBV/ENTA—Do you concur with the SAPHIRE-1/2 expectations in #msg-92714916? If not, why not? T.i.a.

Anyone else may chime in here.