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Re: pcrutch post# 167605

Saturday, 10/05/2013 3:08:44 PM

Saturday, October 05, 2013 3:08:44 PM

Post# of 257661
ABBV/ENTA—I expect SVR12 >=95% for SAPHIRE-1 and SVR12>=90% for SAPHIRE-2 in the immediate-treatment arms.

In each trial, I expect the immediate-treatment arm and the delayed-treatment (control) arm to have roughly the same SVR rate, although the delayed-treatment arms could have slightly lower SVR rates due to the possibility of non-drug-related discontinuation during the 12-week placebo period.

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