The only reason I can think of the FDA not following a positive Adcom recommendation is that it believes that reducing trig levels between 200-500 is completely useless medically and thus a waste of money and effort. I don't see that happening .
I don't either - my TGs never got over 500 back in the years my PCP tortured me with all the nasty drugs, they were only around 300-350, which elevated TC, which is what he tried to treat. There is absolutely no reason for the Adcom not to vote yes.