Replies to post #19420 on Biotech Values

[Praveen]

Thanks so much Fid.I wanted to get a start and I don't know any newsletter which covers canadian bio. I don't mind investing in stable stocks in canadian technology and others, but my time won't allow me to research them. So I just invest in canadian bio as I feel the mutual funds are not upto my investment style.

I am right now in Gatineau, the beautiful french province on the other side of Ottawa. As I don't know French, I find it a little tough but the people here and the location is amazing.

Thanks again,
Praveen

[Praveen]

Anormed, Conjuchem

Hi Fid,

I would like to know your thoughts on ConjuChem DAC GLP-1 and Anormed's MOZOBIL,which had good data in the stem cell transplant arena.

Thanks,
Praveen

[DewDiligence]

Yet another potential player in AMD,
although the initial ophthalmic indication
for this drug will be posterior uveitis.

http://biz.yahoo.com/prnews/060525/to207.html?.v=26

>>
Isotechnika signs agreement granting Lux Biosciences Worldwide Ophthalmic rights to ISA247

EDMONTON, May 25 /PRNewswire-FirstCall/ - Isotechnika Inc. announced today that the Company has signed an agreement with Lux Biosciences, Inc. of Jersey City, New Jersey granting Lux Biosciences worldwide rights to develop and commercialize Isotechnika's lead drug, ISA247 for the treatment and prophylaxis of all ophthalmic diseases.

ISA247 is a novel calcineurin inhibitor currently being investigated in a Phase III trial for the treatment of moderate to severe psoriasis and a Phase IIb trial for the prevention of organ rejection following transplantation.

Under the terms of the agreement:

- Lux Biosciences, Inc. will make upfront and milestone payments to Isotechnika. Assuming all development milestones are achieved, the
amount of this deal will be $32,700,000 USD with Isotechnika receiving an upfront payment of $3 million USD.
- Lux Biosciences, Inc. will pay Isotechnika royalties based on a percentage of net sales.
- Lux Biosciences, Inc. has exclusive worldwide marketing rights of
ISA247 for all ophthalmic indications.
- Lux Biosciences, Inc. would be responsible, at its sole expense, for pre-clinical and clinical development, registration, and marketing of ISA247 for all ophthalmic indications.
- Isotechnika will be providing input on clinical trial design and will be reviewing and consulting on all regulatory filings.
- A Joint Steering Committee ("JSC") with equal membership from Isotechnika and Lux Biosciences, Inc. will be formed to oversee
the development and commercialization of all ophthalmic indications.

"This agreement reconfirms the versatility of ISA247 as a multi-platform technology," stated Dr. Randall Yatscoff, Isotechnika's President and Chief Executive Officer. "Lux Biosciences' team has extensive experience in this area and we are extremely pleased to have them as a partner. We believe this agreement provides us with another opportunity to optimize shareholder value."

Dr. Ulrich Grau, Lux Biosciences' President and CEO comments, "We are delighted to be able to partner ISA247 for ophthalmic indications, and I commend Isotechnika for its great efforts behind its flagship molecule. We are highly impressed with the emerging profile of ISA247 that combines efficacy with superior safety. We believe that ISA247 has the potential to become the calcineurin inhibitor of choice with great potential in several indications, including ophthalmic indications."

Dr. Randall Yatscoff will chair a web cast this morning to provide an overview of the agreement. The web cast will take place at 9:00 a.m. ET/ 7:00 a.m. MT. All interested parties can access the live web cast (listen only mode) by accessing http://www.newswire.ca/en/webcast/viewEvent.cgi?eventID(equal sign)1497760 or through the home page of the Company's corporate Web site at www.isotechnika.com.
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