Aztra Zeneca coducted different study. Official Title: A Phase II, Double-blind, Randomised Study to Assess the Efficacy of AZD6244 in Combination With Dacarbazine Compared With Dacarbazine Alone in First Line Patients With BRAF Mutation Positive Advanced Cutaneous or Unknown Primary Melanoma http://clinicaltrials.gov/ct2/show/NCT00936221?term=selumetinib&cond=melanoma&phase=1&rank=6
Different BRAF mutation status, different primary endpoints.