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Re: mcbio post# 151792

Monday, 11/05/2012 10:13:45 PM

Monday, November 05, 2012 10:13:45 PM

Post# of 257448
It is University of Oxford study.
Official Title: A Double Blind Randomised Phase 2 Trial of Docetaxel With or Without AZD6244 in wt BRAF Advanced Melanoma
http://clinicaltrials.gov/ct2/show/NCT01256359?term=selumetinib&cond=melanoma&phase=1&rank=4

Aztra Zeneca coducted different study.
Official Title: A Phase II, Double-blind, Randomised Study to Assess the Efficacy of AZD6244 in Combination With Dacarbazine Compared With Dacarbazine Alone in First Line Patients With BRAF Mutation Positive Advanced Cutaneous or Unknown Primary Melanoma
http://clinicaltrials.gov/ct2/show/NCT00936221?term=selumetinib&cond=melanoma&phase=1&rank=6

Different BRAF mutation status, different primary endpoints.

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