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skitahoe

11/05/12 4:07 PM

#2375 RE: Globaltrnr #2374

I hope you're right about initiating the Phase III this year, I really don't expect it till 1st quarter of next. I agree with your others and also believe we could hear about Cancer Cachexia by 2nd or 3rd quarter of next year.

It's the norm in biotechs for delays to result in forecasts not quite being met. What's important is that we get some positive news, though not every drug they create can possibly be successful. We may need to take the bitter with the sweet, but we do need some of the sweet. Many of the drugs we have under development are potentially blockbusters, we don't need them all, but we do need one, eventually.

Gary
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chmcnfunds

11/05/12 5:10 PM

#2376 RE: Globaltrnr #2374

Also:

1 Not yet recruiting Phase 2 Trial of AEZS-108 in Chemotherapy Refractory in Triple Negative Breast Cancer
Condition: Breast Cancer
Interventions: Drug: Zoptarelin doxorubicin; Drug: paclitaxel; Drug: nab-paclitaxel; Drug: eribulin; Drug: pegylated liposomal doxorubicin; Drug: vinorelbine; Drug: gemcitabine; Drug: capecitabine
2 Recruiting Doxorubicin-GnRH Agonist Conjugate AEZS-108 in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer
Conditions: Prostate Cancer; Hormone-resistant Prostate Cancer; Recurrent Prostate Cancer; Stage IV Prostate Cancer
Interventions: Other: laboratory biomarker analysis; Other: questionnaire administration; Drug: doxorubicin-GnRH agonist conjugate AEZS-108
3 Completed
Has Results Cetrorelix Pamoate IM Regimens in Patients With Symptomatic Benign Prostatic Hyperplasia (BPH)
Condition: Benign Prostatic Hypertrophy
Intervention: Drug: Cetrorelix Pamoate
4 Recruiting A Phase I/II Trial of AEZS-108 in Urothelial Cancer Patients Who Failed Platinum-chemotherapy
Condition: Urothelial Carcinoma
Interventions: Drug: AEZS-108; Drug: AEZS-108 at MTD
5 Completed Investigation of a New, Oral Growth Hormone Secretagogue, Macimorelin (AEZS-130) as a Growth Hormone Stimulation Test.
Condition: Diagnosis of Adult Growth Hormone Deficiency (AGDH)
Intervention: Other: macimorelin as a diagnostic
6 Completed Antitumoral Activity and Safety of AEZS-108 in Women With LHRH Receptor Positive Gynecological Tumors
Conditions: Ovarian Cancer; Endometrial Cancer
Intervention: Drug: AEZS-108
7 Completed
Has Results Cetrorelix Pamoate in Patients With Symptomatic Benign Prostatic Hypertrophy (BPH)
Condition: Benign Prostatic Hypertrophy
Interventions: Drug: Cetrorelix 78+78; Drug: Cetrorelix 78 + Placebo; Other: Placebo
8 Recruiting Pilot Clinical Trial of Repeated Doses of Macimorelin to Assess Safety and Efficacy in Patients With Cancer Cachexia
Condition: Cancer Cachexia
Interventions: Drug: Macimorelin; Drug: Placebo
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http://www.clinicaltrials.gov/ct2/results?term=aezs&Search=Search

AEZS