Well that is convenient. I'm thinking company backs up what they have been saying with substantial time money and research. Why not be indignant in the face of a post that is little more than a rumor? After all, most here are aware of risk. I find your post irresponsible.
I for one appreciate your input, however a little more info would be nice, i am curious as to what exactly he thought would cause an adverse reaction. At the end of the day my confidence in the science is built from my confidence in a brilliant mind that has already been there and done that as far as bringing billion dollar cancer drugs to the market.
And also - he reached opinion without accumulated data of human cytochrome pathway activity and related metabolization and excretion activity. That's what I'm waiting for now and it will be huge info - but the rats do give us a clue (more so than the dogs) and they tolerated extremely well with scant evidence of toxicity - so I do think friend is off the mark. It's not accumulating in healthy cells. It's not causing apoptosis in healthy cells. It does not have extended half life. It did not cause any lifethreatening alteration of blood counts even at highest dosages in rats or dogs (very unusual for antitumor agents and significant sign of low toxicity). Now we'll see how human enzymatic pathways take care of it.