And also - he reached opinion without accumulated data of human cytochrome pathway activity and related metabolization and excretion activity. That's what I'm waiting for now and it will be huge info - but the rats do give us a clue (more so than the dogs) and they tolerated extremely well with scant evidence of toxicity - so I do think friend is off the mark. It's not accumulating in healthy cells. It's not causing apoptosis in healthy cells. It does not have extended half life. It did not cause any lifethreatening alteration of blood counts even at highest dosages in rats or dogs (very unusual for antitumor agents and significant sign of low toxicity). Now we'll see how human enzymatic pathways take care of it.