Replies to post #138375 on Biotech Values

[Summer2762]

On DMC.

If the futility boundary is binding, the co can recover some of the alpha spent on efficacy. If the boundaries are asymmetrical, that might explain the lack of alpha spent.

I am trying to see if the futility can be even stricter than OBF (p>~0.5 @3/4).

And you are right. DMC can stop the trial anytime.