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Summer2762

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Summer2762

Re: DewDiligence post# 138375

Wednesday, 03/07/2012 4:29:08 PM

Wednesday, March 07, 2012 4:29:08 PM

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On DMC.

If the futility boundary is binding, the co can recover some of the alpha spent on efficacy. If the boundaries are asymmetrical, that might explain the lack of alpha spent.

I am trying to see if the futility can be even stricter than OBF (p>~0.5 @3/4).

And you are right. DMC can stop the trial anytime.

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