Replies to post #118828 on Biotech Values

[DewDiligence]

Nevertheless, BG-12 is not the same drug as Fumaderm, just as Teva’s ‘low-volume’ Copaxone (rejected by FDA) is not the same drug as Copaxone.

[genisi]

Fumaric acid itself is poorly absorbed in the body however, Fumaderm is an enteric-coated tablet containing a mixture of dimethyl fumarate and calcium, magnesium, and zinc salts of fumaric acid monomethyl ester. Problem with this formulation is not absorption PO but side effects (GI-related and flushing) that cause a high rate of non-compliance.