News Focus
News Focus
icon url

iwfal

02/18/11 2:02 PM

#115112 RE: dewophile #115104

but i think it is just the opposite - when a tumor invades bone it triggers an increase in turnover, measured as a hot spot on bone scan. when you remove the insult to bone the bone heals itself by LOWERING the rate of remodeling (my understanding is that remodeling = loss of bone, and vice vera,regardless of etiology)



You are assuming that bone scan measures the removal (i.e. a dye that concentrates in osteoclasts). I assume it measures the new bone. The 'dye' is, after all, phosphorus which would be incorporated into new bone. I see no reason why it should concentrate in osteoclasts, which will be getting their phosphorus from the existing (non-radioactive) bone. ??



But both of us are 'assuming' and I was unable to find an authoritative source to decide. (Most web sources are wildly inane on this topic)