I would expect chirality to be one of the easiest things to get right
That is not obvious to me - the two techniques I've seen to distinguish chirality were:
a) Expensive (x-ray crystalography) Or b) Require a different molecular entity with which you know only one chirality responds - but that requires knowing 'receptors' for little spike in the mass spectrogram.
Is there some more general methodology that is proven and cheap-ish?