Biotech Values

[iwfal]

I would expect chirality to be one of the easiest things to get right

That is not obvious to me - the two techniques I've seen to distinguish chirality were:

a) Expensive (x-ray crystalography)
Or
b) Require a different molecular entity with which you know only one chirality responds - but that requires knowing 'receptors' for little spike in the mass spectrogram.

Is there some more general methodology that is proven and cheap-ish?