Eventually, but mainly to the girls. He always stood off from the guys, which was who Furball preferred. Odd though, when Furry died Cuddles became more tolerant of the men in the house. But any other animals or any strangers in the house... he'd run from human strangers and attack if they cornered him. He'd just attack any other animals. When the cats were kittens we had them declawed, front and back. Furry was always a coward so he'd always run, but Cuddles... man oh man. We'd take the cats outside for fresh air, always supervised.
One day two fully grown Rotts came running around the house barking and growling. I went to intervene before they could get to my cats, but Cuddles was a damn sight faster. He started smacking the crap out of them and had them running before I could get across the yard to get between the dogs and the cats, and had them turned tail. I don't think the dogs were in the yard more than 10 seconds, and he almost chased them down the road. Luckily he stopped when I called him back.
About a year later, I was at work and the wife was sleeping in. When she woke up, she found Cuddles sitting next to a 3-4 foot long snake that had gotten in the house. The snake was dead, and was chewed from one end to the other, almost flat. No idea what kind of snake it was, and the wife said the cat was looking so proud he was almost floating off the floor.
Even in his old age he's been a monster. About 2 years ago I had him outside for some grass eating, when the neighbor's 3 year old outside, fully clawed tomcat comes around the corner, and it was on! Cuddles hauled ass to the cat and attacked, and the other cat tried to run. Cuddles tackled the other cat at a full gallop, and it was just a ball of fur rolling towards the privacy fence. The other cat managed to disengage and run up the fence and out of the yard. There was a line of fur, and I mean thick pieces, and not a bit of it belonged to Cuddles.
Still, to family members he was just as loving as a cat could be, before he fell sick. Now, he just lays in front of the litter box staring at the wall, eating almost nothing, and he's down on his weight by almost half. I just don't think he's going to make it, but we're going to keep trying to the end.