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jbog

09/19/10 7:17 PM

#104581 RE: DewDiligence #104580

Dew,

With Bayer releasing more Xarelto data (AF) in November, would you suspect that the whole Lovenox franchise is in danger?

Makes you wonder if the street thinks that Momenta spent years to create dead horse.
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jq1234

09/19/10 9:29 PM

#104594 RE: DewDiligence #104580

On the primary safety endpoint of major bleeding, Apixaban was not statsig worse than aspirin; the hazard ratio was 1.14 and the 95% CI was [0.74,1.75].



That's true, but it is not noninferior either. The sample size (5600 patients) may not big enough in this case. If it mains same percentage 1.4 vs 1.2 in ARISTOTLE trial (18,000 patients), it most likely will be stat sig.

Agree result is great so far.