News Focus
News Focus
Post# of 257253
Next 10
Followers 69
Posts 4516
Boards Moderated 0
Alias Born 12/13/2009

Re: DewDiligence post# 104580

Sunday, 09/19/2010 9:29:50 PM

Sunday, September 19, 2010 9:29:50 PM

Post# of 257253

On the primary safety endpoint of major bleeding, Apixaban was not statsig worse than aspirin; the hazard ratio was 1.14 and the 95% CI was [0.74,1.75].



That's true, but it is not noninferior either. The sample size (5600 patients) may not big enough in this case. If it mains same percentage 1.4 vs 1.2 in ARISTOTLE trial (18,000 patients), it most likely will be stat sig.

Agree result is great so far.

Trade Smarter with Thousands

Leverage decades of market experience shared openly.

Join Now