Replies to post #103266 on Biotech Values

[jellybean]

There are two melatonin receptors in humans, one is involved in sleep regulation and the other in sexual physiology. Over the counter melanonin drives both receptors. Vanda's logic was to focus only on the sleep receptor.

[genisi]

Why not just use melatonin?

First because melatonin has a short half-life also it was only effective for mild cases in blind people with Non-24-Hour Sleep Wake Disorder.