I have no need to comment further onn Agilyx's patent if we operate under atmospheric pressure - with or without an inert nitrogen purge. Taking away a claimed element of a system or method patent does not infringe. Adding an element (eg the catalyst) but still using all of the claimed elements does.
Note that if you add an element but use all of the elements, you have protection against others adding that element but you still infringe on the prioi patent.
The patent is a dead issue - other than to remind us that, with enough subtext after "comprising" a new patent can be obtained.