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Replies to #93622 on Biotech Values

dewophile

04/04/10 7:41 PM

#93655 RE: DewDiligence #93622

INHX’s INX-189 is very similar to IDIX’s IDX184 in structure and MoA; both are prodrugs of a monophosphate nucleotide analog of guanosine



it is so similar i wonder if the INHX compound runs into some IP issue - IDIX seems to have pretty extensive patents around 184

DewDiligence

05/13/10 7:12 AM

#95682 RE: DewDiligence #93622

INHX’s INX-189 has started phase-1:

http://finance.yahoo.com/news/Inhibitex-Reports-First-bw-1492284419.html?x=0&.v=1

The Company announced that it has initiated a Phase I double-blind, placebo-controlled, single ascending dose study to evaluate the safety and pharmacokinetics of INX-189 in healthy volunteers… The study, which is being conducted in the U.S., will evaluate up to six escalating doses of INX-189, ranging from 3 mg up to 200 mg. Each dose cohort will include eight subjects, six of which will receive INX-189 and two that will receive placebo.

As noted in #msg-48567678, INX-189 is similar to IDIX’s IDX184 in structure and MoA.