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Re: gfp927z post# 93467

Saturday, 04/03/2010 10:54:20 PM

Saturday, April 03, 2010 10:54:20 PM

Post# of 252331
INHX’s INX-189 is very similar to IDIX’s IDX184 in structure and MoA; both are prodrugs of a monophosphate nucleotide analog of guanosine. This is the short write-up on INX-189 from INHX’s website:

http://www.inhibitex.com/Pipeline/Hepatitis.htm

The key distinction between the IDX184 and INX-189 programs is timing: INX-189 has not yet entered phase-1, and hence IDX184 is further advanced by about two years. INX-189 is about even in timing with VRUS’ PSI-938, another drug with the same general structure (#msg-39322313).


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