Replies to post #75504 on Biotech Values

[dewophile]

I too am not convinced clevudine will achieve SVR, but my point is if it does and there is a paradigm shift to achieve SVR then interferon combination should increase the rate of cure more than combination with other nukes because interferon as monotherapy already has a measurable (albeit low) SVR as monotherapy compared with a negligible rate for nukes. on the other hand, if chronic suppression of virus remains the goal for most then perhaps combos of 2 nukes will become popular to decrease resistance, although there will be a lot of scrutiny on safety and cost-effectiveness, especially since viread and baraclude have inhernently high barriers to resistance as monotherapy - especially in naive pts