Dew, although I have been unpleasantly reminded that a good understanding of science is not enough to earn money in the biotech investing field I still belive that it can help you find god investments. At least in the long run.. I happen to believe that the science of Oxigene is solid and that they have thoroughly explained zybrestats MOA. Hypoxia is a problem for all "blood starving" approaches and I don't understand what you mean with "The point being that these newfangled MoA acronyms in and of themselves don’t mean squat." Could be because I'm a Swede.. Regards nuere