For what it's worth, i think TDM-1 will be on the market in 4yrs. I also think it has an 80% chance of getting to market, but i think the sales ramp may be slower than some think. I think it may eventually hit $1B, but will take at least 4-5 yrs on market to see that. So 8 yrs from now, the product may see $1B in sales.